Hallucinations as an adverse effect of angiotensin converting enzyme inhibition.

Hallucinations as an adverse effect of angiotensin converting enzyme inhibition.

Hallucinations as an adverse effect of angiotensin converting enzyme inhibition Sir, We describe two cases of disturbed visual perception during treatment of heart failure with captopril and enalapril. A 73 year old man was commenced on enalapril 5 mg twice a day when he developed pulmonary oedema 2 months after an anterior myocardial infarction. His only other medications were frusemide 80 mg ...

Angiotensin Converting Enzyme in Sarcoidosis

Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2.

BACKGROUND Angiotensin-converting enzyme 2 (ACE2) has emerged as a novel regulator of cardiac function and arterial pressure by converting angiotensin II (Ang II) into the vasodilator and antitrophic heptapeptide, angiotensin-(1-7) [Ang-(1-7)]. As the only known human homolog of ACE, the demonstration that ACE2 is insensitive to blockade by ACE inhibitors prompted us to define the effect of ACE...

Role of Tissue Angiotensin-Converting Enzyme Inhibition

Background Chronic treatment with high doses of angiotensin-converting enzyme (ACE) inhibitors prolongs survival after myocardial infarction. Since the plasma reninangiotensin system (RAS) is not consistently activated in the chronic phase after myocardial infarction, the beneficial effects of ACE inhibition have been attributed, in part, to inhibition of an activated tissue RAS. However, a rel...

Effects of Chronic Angiotensin Converting Enzyme Inhibition

Background. Previous studies have shown that global left ventricular function is depressed after myocardial infarction. However, little is known about the effects of myocardial infarction on contractility and the passive-elastic properties of residual myocardium. Methods and Results. We evaluated isometric function and passive myocardial stiffness in isolated, noninfarcted left ventricular papi...